Beyond Biopharma Co.,Ltd.
Collagen Manufacturer
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Chicken Sternum Cartilage Extract with Native Collagen type ii for Joint Care Supplements
We Beyond Biopharma produce and supply native collagen type ii extracted from chicken sternum cartilages.
What is Chicken sternum cartilage extract with native collagen type ii ?
Chicken sternum cartilage extract is a protein powder mixture which contains native collagen type ii and other nutrtional substances such as chondroitin sulfate, glucosamine and hyaluronic. Due to the high content of collagen type ii, the extract is commonly known as collagen type ii powder. The extract is also know as undenatured collagen powder or native collagen type ii because the collagen type ii in the chicken sternum extact is native and undenatured.
What extactly is that undenatured type ii collagen in the chicken sternum cartilage extract ?
Actually, chicken sternum contains abundant type ii collagen. But how to extact and stablize that collagen type ii is a challenge because the protein of the collagen is easily denatured or lost its activity when it is heated or boiled. The type ii collagen will also lost its activity if it is in contact with strong acid or alkaline solvents.
The above two challenges makes the purification of undenatured type ii very difficult. But we Beyond Biopharma had developed an manufacturing technique to obtain the native type ii collagen from chicken sternum cartilages while at the same time maintain the activity of the type ii collagen.
Below is the manufacturing process of undenatured type ii collagen from chicken sternum cartilage. Since this is a patented manufacturing process, we don't disclose all the details of the manufacturing process, Please kindly understand.
| Chicken Sternum |
| → |
| Pre-treatment(removing tissues and wash the cartilages) |
| → |
| Milling (cut the sternum cartilages into small pieces) |
| → |
| Remove the other unnecessary proteins |
| → |
| Washing |
| → |
| Sterilization(add high concentration of alcohol) |
| → |
| Centrifugation (Remove the ethanol) |
| → |
| Drying Process (Under the low temperature below 40℃) |
| → |
| Milling and Sifting |
| → |
| Metal detector |
| → |
| Inner packing |
| → |
| Outer packing |
| → |
| Analytical Testing |
| → |
| Undenatured Chicken Collagen Type II |
The content of native collagen in the undenatured collagen type ii varies from 5% to 25%. We can supply different purities according to your needs such as 5%, 10%, 15%, 20% or 25%. Blow is a typical specification sheet of undenatured collagen type ii with 10% native collagen type ii.
Specification of Undenatured Collagen type II
| PARAMETER | SPECIFICATIONS | Test Method |
| Appearance | White to off white powder | Visual |
| Origin of Material | Chicken Sternum | N/A |
| Total Protein Content | ≥60% | <Kjeldahl method> |
| Undenatured Collagen type II | ≥10.0% | <Elisa Method> |
| pH | 5.5-7.5 | <USP791> |
| Residual on Ignition | ≤35% | <USP281> |
| Loss on drying | ≤10.0% | <USP731> |
| Heavy Metal | ＜ 20 PPM | <ICP-MS> |
| Lead | ＜1.0mg/kg | <ICP-MS> |
| Mercury | ＜0.1mg/kg | <ICP-MS> |
| Cadmium | ＜1.0mg/kg | <ICP-MS> |
| Arsenic | ＜0.1mg/kg | <ICP-MS> |
| Particle size | 100% pass 80 mesh | In-house Method |
| Bulk density | Report as it is | In-house method |
| Total Bacteria Count | ＜1000cfu/g | <USP2021> |
| Yeast & Mold | ＜100cfu/g | <USP2021> |
| E.Coli | Absence/g | <USP2022> |
| Salmonella | Absence/25g | <USP2022> |
| Staphylococcus aureus | Absence/g | <USP2022> |
The importance of Type ii Collagen for our joint health
Type ii collagen contains various types of amino acids that are needed by human body. Especially there is one type of amino acid called hydroxyproline which our body can't produce by ourself. This means we need to additionally supply this amino acids from our foods or dietary supplements products. Undenatured type ii collagen is a great source of hydroxyproline. Besides hydroxyproline, type ii collagen also provides other types of amino acids. Below is a composition table of amino acids in the native type ii collagen.
Amino acid composition of undenatured collagen type ii:
| Amino acids | Typical g AA in 100g undenatured collagen type II |
| Alanine | 8.0 |
| Arginine | 8.5 |
| Aspartic acid | 4.9 |
| Cystine | 0 |
| Glutamic acid | 11.1 |
| Glycine | 20.0 |
| Histidine | 1.3 |
| Hydroxylysine | 1.5 |
| Hydroxyproline | 10.1 |
| Isoleucine | 1.5 |
| Leucine | 2.5 |
| Lysine | 3.3 |
| Methionine | 0.8 |
| Phenylalanine | 2.3 |
| Proline | 12.1 |
| Serine | 3.3 |
| Threonine | 2.6 |
| Tryptophan | 0 |
| Tyrosine | 0.4 |
| Valine | 1.9 |
We have several other documentations such as Nutritional Value, MSDS, Technical Data Sheet of undenatured collagen type II available. If you want to know more about this product, please kindly send a inquiry, we will get back to you as soon as possible.
What are the applications of undenatured type ii chicken collagen ?
Traditionally, the undenatured collagen type II is used to produce hard capsule containing 40mg native collagen type II. The dosage is suggested to be one capules per day. But there are some more and more customers use our undenatured collagen type II to produce other finished dosage forms such as Tablets or softgel, or Solid drinks in sachets or Cans.
Our undenatured collagen is suitable to produce in various types of finished dosage forms. But all these finished dosage forms have one thing in common, that is for Joint Health only.
Commercial Terms:
Packing: Our packing is 25KG/Drum for big commercial orders. For small quantity order, we can do packing like 1KG,5KG, or 10KG, 15KG in a Aluminum foil bags.
Sample Policy: We can provide up to 30 grams free of charge. We usually send the samples via DHL, if you have a DHL account, please kindly share with us.
Price : We will quote the prices based on different specifications and quantities.
Custom Service: We have dedicated sales team to deal with your inquiries. We promise you will sure get a response within 24 hours since you send a inquiry.